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Link Between Diabetes And TB Discovered


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11/17/2008
Brent Adams
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According to a recent study, patients who suffer from the disabling condition of Type 2 diabetes could be at risk of contracting tuberculosis (TB) due to a compromised immune system.

According to researchers at the University of Texas School of Public Health Brownsville Regional Campus, the effect could cause life-threatening lung infections that are more difficult to treat.

The researchers led three studies which revealed that Type 2 diabetes, cases involving chronic high blood sugar in particular, is associated with altered immune response to TB. Patients who suffer from diabetes and TB take more time to respond to anti-TB treatment and have a higher likelihood of multi-drug resistant TB.

The researchers discovered that innate and type 1 cytokine responses were significantly higher in TB patients who also suffered from diabetes than patients who have TB but not diabetes.

The effect consistently and significantly showed up more in diabetic patients who had chronic hyperglycemia (uncontrolled high blood sugar).



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